In Newfoundland, 5,422 moose-vehicle collisions (MVCs) occurred between 1988 and 1994, resulting in 14 human and approximately 4,800 moose (Alces alces) fatalities. The authors examined daily, seasonal, and spatial distribution patterns of MVCs and used log-linear modeling to assess effects of darkness, posted speed limits, road condition, vehicle occupants, and road alignment on severity of human injury resulting from such collisions. Seventy-five percent of all MVCs occurred between dusk and dawn.